Scottish synthetic bone graft company secures £3million funding

Published: 5 December 2014

Synthetic bone graft technology firm Sirakoss has secured more than £3m in funding from a syndicate of investors. This equity investment also secures a further £940,000 Biomedical Catalyst award from Innovate UK.

SIRAKOSS, a medical device company based in Edinburgh and Aberdeen, has developed synthetic bone graft substitutes that will revolutionise the treatment of bone defects and fusions. 

Synthetic bone grafts are used in trauma, spinal and dental surgery to fuse bones together to correct congenital or degenerative conditions (such as curvature of the spine) or following a traumatic injury where the bone fails to heal.

The alternative approach against which all other options are measured is autograft - this is where healthy bone is harvested from the patient’s hip and replanted at the defect site. The amount of bone that is available for grafting is limited, particularly in children, and requires two invasive operative procedures, increasing the risk for the patient and the cost for the hospital. Other alternatives have seen products derived from cadaver bone harvested at the morgue, but these can be inconsistent in their performance.

The SIRAKOSS MaxSiTM Graft range of products is entirely synthetic, containing no animal or human tissue and can be manufactured in consistent, high quality batches. Screening studies with the MaxSiTM Graft products from SIRAKOSS demonstrate rapid, controlled bone formation at very early time points, indicative of early patient recovery. Surgeons’
feedback on performance data and handling properties of the SIRAKOSS material, whencompared to existing products, has been very encouraging.

Other syndicate members include the Scottish Investment Bank, the investment arm of Scottish Enterprise, and the London-based Worshipful Company of Armourers & Brasiers plus existing shareholders. This equity investment also secures a further £940,000 Biomedical Catalyst award from Innovate UK (formerly known as the Technology Strategy
Board), which was previously awarded to SIRAKOSS in a competitive funding programme and was subject to matching investment.

Brian Butchart, CEO of SIRAKOSS commented, “We are delighted to have closed this investment with Epidarex Capital as this validates the company’s belief in its outstanding and highly differentiated synthetic bone graft technology and the clearly defined commercial opportunity that this represents within a $2.5bn global market. This investment will enable SIRAKOSS to complete product development and to implement its regulatory strategy for
both the European and US markets”.

Sinclair Dunlop, Managing Partner at Epidarex Capital stated “Epidarex is delighted to be leading the current financing of SIRAKOSS. The company’s core technology offers several novel and potentially disruptive applications in the global synthetic bone graft market. We are very excited about the company’s prospects”.

Professor Bill Bonfield, chairman of the Armourers & Brasiers Venture Prize panel said, “We were hugely impressed with the SIRAKOSS technology which can offer surgeons a materials science alternative to pharmacological products for obtaining rapid bone repair and fusion.

The company has also recognised the importance of melding both scientific and commercial  skills sets. The SIRAKOSS technology has the potential to benefit thousands of people each year and it also fits well with our aim to encourage innovative scientific entrepreneurship in the UK.”

Eleanor Mitchell, Director of Commercialisation, Scottish Enterprise, said “Congratulations to SIRAKOSS for securing this investment deal, allowing it to further realise its ambitious scaling plans both in Europe and the USA. Scottish Enterprise has assisted throughout the journey with an integrated package of support, including early proof of concept activities at the University of Aberdeen, and later the company with SMART: SCOTLAND grant support for feasibility testing, assistance in scaling up in global markets and most recently, investment via the Scottish Investment Bank.

Scottish Enterprise works closely with Epidarex and views this fund as a key asset to Scotland’s life sciences companies therefore we are delighted that they will be supporting the growth of SIRAKOSS.”


For further information contact

Brian Butchart


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